Chapter 5 Principles Of Anatomy And Physiology Flashcards ionicons-v5-c

Integumentary system

System that is composed of the skin, hair, oil, sweat glands, nails, and sensory receptors

Dermatology

Medical specialty that deals with the structure, function, and disorders of the integumentary system

Cutaneous membrane

Covers the external surface of the body and is the largest organ of the body in weight. It's your skin

Epidermis

Superficial, thinner portion of integumentary system; composed of epithelial tissue; composed of keratinized stratified squamous epithelium

Dermis

The deeper, thicker connective tissue portion of integumentary system

Subcutaneous layer

Deep to the dermis, but not part of the skin. Consists of areolar and adipose tissues. Also called hypodermis

Lamellated Corpuscles

Nerve endings, Sensitive to pressure. Also known as pacinian

Pacinian corpuscles

Nerve endings, Sensitive to pressure. Also known as Lamellated

Keratinocytes

Type of epidermal cells, which are arranged in four or five layers and produce the protein keratin

Keratin

Type of protein, it is tough, fibrous and helps protect the skin and underlying tissues from abrasions, heat, microbes, and chemicals

Melanocytes

Epidermis cells which develop from the ectoderm of a developing embryo and produce the pigment melanin

Melanin

Yellow-red or brown-black pigment that contributes to skin color and absorbs damaging ultraviolet light

Langerhan cells

Cells that arise from red bone marrow and migrate to the epidermis, where they constitute a small fraction of the epidermal cells. They participate in immune responses mounted against microbes that invade the skin, and are easily damaged by UV light.

Merkel cells

The least numerous of epidermal cells. They are located in the deepest layer of the epidermis, where they contact the flattened process of a sensory neuron. These play a role in sensations

Merkel discs

Tactile discs that detect touch sensations

Thin skin

Epidermis that has 4 strata or layers. Found in most regions of the bodystratum basalestratum spinosumstratum granulosumthin stratum corneum

Thick skin

Epidermis which gets exposed to much friction and has 5 layersstratum basalestratum spinosumstratum granulosumstratum lucidiumthick stratum spinosum

Stratum basale

The deepest layer of the epidermis, composed of a single row of cuboidal or columnar keratinocytes; some are stem cells, so here cells regenerate. Contains melanocytes and merkel cells

Skin graft

The transfer of a patch of healthy skin taken from a donor site to cover a wound

Stratum spinosum

Superficial to the stratum basale; a bit of reproduction; contain lengerhan cells

Stratum granulosum

Consists of three to five layers of flattened keratinocytes that are undergoing apoptosis, as they are far from their source of nutrition (blood)

Keratohyalin

Granules of protein which assembles keratin intermediate filaments into keratin. Present in stratum granulosum

Lamellar granules

Protein granules which fuse which the plasma membrane and release a lipid-rich secretion. Present in keratinocytes

Stratum lucidum

Layer of epidermis that is present only in the thick skin of areas such as the fingertips, palms, and soles; 4-6 layers of flattened dead keratinocytes

Stratum corneum

Consists on average of 25 to 50 layers of flattened dead keratinocytes; thin, flat, plasma membrane-enclosed packages of keratin that no longer contain a nucleus or any internal organelles

Callus

An abnormal thickening of the stratum corneum, which is the result of friction

Karatinization

A process in which the cells move from one epidermal layer to the next, accumulating more and more keratin

Dandruff

An excessive amount of keratinized cells shed from the skin of the scalp

Psoriasis

chronic skin disorder in which keratinocytes divide and move more quickly from the stratum basale to the stratum corneum; make abnormal keratin that forms scales

Papillary region

Makes up about one-fifth of the thickness of the total dermis. It contains thin collagen and fine elastic fibers

Dermal papillae

small, nipple-shaped structured that project into the undersurface of the epidermis

Capillary loops

All dermal papillae contain these, they are blood vessels. Provide nutrient supply to epidermis too

Meissner corpuscles

Type of nerve endings that are sensitive to touch

Reticular region

Dermis, which is attached to the subcutaneous layer, contains bundles of thick collagen fibers, scattered fibroblasts, and various wandering cells.

Extensibillity

The ability to stretch

Elasticity

The ability to return to original shape after stretching

Epidermal ridges

Straight lines or pattern of loops and whorls (like fingers). Create strong bond between the epidermis and dermis in a region of high mechanical stress. Also increase surface area (grip)

Fingerprints (footprints)

The ducts of sweat glands open on the tops of the epidermal ridges as sweat pores that leave marks on things when you touch. Unique for everyone

Dermatoglyphics

The study of the pattern of epidermal ridges (fingerprints)

Tension lines

(lines of cleavage) in the skin that indicate the predominant direction of underlying collagen fibers

Mole

A benign localized overgrowth of melanocytes. Also known as nevus

Melanosome

Organelle where melanocytes sunthesize melanin. Exposure to UV increases the activity

vitiligo

The partial or complete loss of melanocytes from patches of skin produces irregular white spots

Hemoglobin

The oxygen-carrying pigment in red blood cells. Makes skin pinkish or reddish

Carotene

A yellow-orange pigment that gives egg yolks and carrots their color; found in stratum corneum and fatty areas of dermis and hypodermis. White people eating carrots can turn orange

Cyanotic

bluish skin due to lack of oxygen in skin

Jaundice

Yellow skin due to bilirubin. Usually due to liver disease

Erythema

Redness of skin, due to allergies or burns

Pallor

Paleness of skin. Due to shock or anemia

Accessory structures of the skin

Hair, skin glands, and nails. Develop from embryonic epidermis

Hair

Also pilli; present on most skin surfaces; composed of columns of dead, keratinized epidermal cells bonded together by extracellular proteins

Shaft

superficial portion of the hair, which projects above the surface of the skin

Root

The portion of the hair deep to the shaft that penetrates into the dermis, and sometimes into the subcutaneous layer

Hair follicle

Part of the hair that surrounds the root and is made up of an external root sheath and an internal root sheath

Epithelial root sheath

Part of the hair that extends as a downward continuation of the epidermis. Makes up hair the hair follicle.

Dermal root sheath

The dense dermis surrounding the hair follicle

Bulb

Onion-shaped structure that is at the base of each hair follicle.

Papilla of the hair

Part of the hair bulb, which contains areolar connective tissue and many blood vessels that nourish the growing hair follicle

Hair matrix

Germinal layer of cells in hair contained in the bulb. Responsible for growth and regrowth

Depilatory

A substance that removes hair

Electrolysis

An electric current is used to destroy the hair matrix so the hair can't regrow

Arrector pili

Smooth muscle that are associated with hairs. Pulls on hair when scared or cold - goose bumps

Hair root plexus

dendrites of neurons that surround each hair follicle; generate nerve impulses if their hair shafts are moved

Growth stage

Stage in which the cells of the hair matrix divide. for scalp is 2 to 6 years

Regression stage

When the cells of the hair matrix stop dividing, the hair follicle atrophies, and the hair stops growing. for scalp is 2 to 3 weeks

Resting stage

A stage the hair follicle enters after the regression stage. for scalp is 3 months

Alopecia

Partial or complete lack of hair

Lanugo

Nonpigmented, downy hairs that cover the entire body of fetus

Terminal hairs

Long, coarse, heavily pigmented hairs that replace lanugo in some areas (like eyebrows) right before birth

Vellus hairs

peach fuzz. replace lanugo in most areas before birth. During puberty, these will be replaced by terminal hair in certain areas

Hirsutism

Excessive body hair due to excessive production of androgens

Sebaceous glands

Its your oil glands. Simple branched acinar glands that are attached to hair follicles

Sebum

Substance secreted by sebaceous glands. Triglycerides, cholesterol, proteins, inorganic salts

Acne

An inflammation of sebaceous glands that usually begins at puberty

Sudoriferous glands

Sweat glands. Release sweat or perspiration into hair follicles or into the skin surface through pores

Eccrine sweat glands

Simple, coiled tubular sudoriferous glands that are much more common than apocrine sweat glands. Helps regulate body temperature through evaporation

Thermoregulation

The homeostatic regulation of body temperature is known as ______________________.

Thermoregulatory sweating

The role of eccrine sweat glands in helping the body to achieve homeostasis is known as ____________.

Insensible perspiration

Sweat that evaporates from the skin before it is perceived as moisture

Sensible perspiration

Sweat that is exerted in larger amounts and is seen as moisture

Emotional sweating

Also cold sweat. Occurs when eccrine sweat glands release in response to an emotional stress, such as fear or embarrassment. Occurs first in palms and axillae

Apocrine sweat glands

Simple coiled tubular sudoriferous glands that are found in axilla, groin, nipples. Secretory portion opens to hair folicules.

Ceruminous glands

Produce a waxy lubricaing glands, produce a waxy lubricating secretion

Cerumen

Earwax

Nails

Are plates of tightly packed, hard, dead, keratinized epidermal cells that form a clear, solid covering over the dorsal surfaces of the distal portions of the digits

Nail body

The visible portion of the nail

Free edge

The part of the nail body that may extend past the distal end of the digit

Nail root

The portion of the nail that is buried in a fold of skin

Lunula

the white crescent at the proximal end of the nail body

Hyponychium

Nail bed. Thickened region of stratum corneum beneath the nail bed

Eponychium

Cuticle. Narrow band of epidermis. Consists of stratum corneum.

Nail matrix

the proximal portion of the epithelium deep to the nail root. Nail growth

Inflammatory phase

A phase in deep wound healing where a blood clot forms and loosely unites the wound edges

Inflammation

A vascular and cellular response that helps eliminate microbes, foreign material, and dying tissue in preparation for repair

Migratory phase

A phase of deep wound healing in which the clot becomes a scab, and epithelial cells migrate neneath the scab to bridge the wound.

granulation tissue

A tissue filling the wound during the migratory phase

Proliferative phase

A phase in deep wound healing characterized by extensibe growth of epithelial cells beneath the scab

Maturation Phase

A phase in deep wound healing, in which the scab sloughs off

Fibrosis

A process of scar formation

hypertropic scar

scar that remains within the boundaries of the original wound

keloid scar

A scar tissue that extends beyound the boundaries into normal surrounding tissues

Vernix Caseosa

Fatty substance which covers and protects the fetus from constant exposure to the amniotic fluid